Screening of Microbial Spectrum of Odontogenic Infections & their Antibiotic Sensitivity: A Demographic Cross-sectional Study on Egyptian Patients.

Document Type : Original Article

Authors

1 Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University

2 Department of Immunology and Microbiology, Faculty of Medicine, Cairo University.

Abstract

Aim: This study aimed to investigate the etiology, microbiology, and antibiotic sensitivity profiles of odontogenic infections among patients presenting to the department of oral and maxillofacial surgery at Cairo University.
Subjects and methods: A total of sixty-five patients with odontogenic infections were enrolled over a 40-month period, following thorough preoperative assessments including clinical, radiographic, and bacteriological examinations. Pus samples were collected via aspiration and subjected to aerobic and anaerobic cultures. Bacterial isolates were identified, and antibiotic susceptibility testing was performed. Treatment protocols consisted of surgical interventions such as incision and drainage, coupled with empirical antibiotic therapy tailored to individual patient profiles.
Results: Predominant bacterial isolates included enterococci, streptococci, and staphylococci, with variable susceptibility to commonly used antibiotics. Notably, enterococci exhibited sensitivity to ampicillin and levofloxacin but demonstrated reduced sensitivity to vancomycin. Streptococci showed sensitivity to cefotaxime and linezolid. Penicillin showed an accepted overall sensitivity rate.
Conclusion: Aerobic bacterial isolates were predominantly found, notably enterococci, differing from some international studies and emphasizing the need for region-specific research in clinical practice. Antibiotic sensitivity varied among isolates, with penicillin group antibiotics showing promise as first-line treatments, but caution advised.

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Advanced Dental Journal
Volume 7, Issue 3
July 2025
Pages 386-396

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