Radiographic assessment following maxillary bone augmentation using patient specific titanium meshes loaded with bone marrow aspirate mixed with xenograft versus xenograft mixed with autografts only: a randomized clinical trial.

Document Type : Original Article

Authors

1 Faculty of Dentistry, The British University in Egypt, Cairo, Egypt

2 Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University, Egypt

3 Oral and Maxillofacial Surgery, Faculty of dentistry, The British University in Egypt, Cairo, Egypt

4 Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University, Cairo, Egypt

Abstract

Abstract
Purpose: The aim of the study is to evaluate the efficacy of three-dimensional bone augmentation in maxillary atrophied alveolar ridges by comparing the utilization of bone marrow aspirate concentrate along with a mix of autograft and xenograft versus autograft and xenograft alone. utilizing patient-specific titanium meshes.
Methods: Ten patients experiencing severe vertical and horizontal deficiencies in the entire maxillary arch underwent guided bone regeneration. Utilizing specialized software, virtual bone augmentation were performed for the deficient ridge across the entire maxillary alveolus. This process involved generating virtually augmented models to guide the preoperative prebending of titanium meshes. In the study group, prebent meshes were filled with a combination of xenograft and bone marrow aspirate concentrate (BMAC). Conversely, in the control group, the meshes were loaded with xenograft mixed solely with autograft in a 1:1 ratio.
Results: All patients experienced uneventful wound healing. Six months postoperatively, Cone Beam Computed Tomography (CBCT) scans were conducted for each patient, revealing a higher Mean vertical bone gain in the Study group (3.46 ± 0.89 mm) while the Control group showed (2.57±0.96 mm). The Mean horizontal bone gain in the Study group (3.80±1.20 mm) while the Control group was (3.91±0.89 mm).
Conclusion: The difference between the study and control group in both vertical and horizontal bone gain was not statistically significant. Three-dimensional bone augmentation using prebent titanium meshes loaded with xenograft with bone marrow aspirate concentrate could be a reliable less morbid technique.

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