Evaluation of the Antibacterial Activity, Solubility and Ions Release of Compomer before and after the Addition of 0.025 ml Silver Nanoparticles: An In-Vitro Study

Document Type : Original Article

Authors

1 Biomaterials Department, Faculty of Dentistry, Cairo University, Egypt

2 Biomaterials Department, Faculty of Dentistry, October 6 University, Egypt

Abstract

Aim: Evaluate the effect of silver nanoparticles addition on antibacterial activity, solubility and ions release of compomer at different time intervals. Methodology: 0.025 ml nanosilver alcohol solution (5000 ppm) was mixed with 2 g of Composan glass (compomer material). Composan glass without nanosilver was used as the control group. Total of 48 disc-shaped samples(15x1mm) were prepared and immersed in distilled water for 24 hours, 1 and 3 months. After each time interval, samples were assessed for antibacterial activity by Agar Diffusion Test using Streptococcus mutans. Water sorption and solubility were evaluated by weighting the samples before and after immersion. Fluoride Ion-Selective Electrode determined fluoride release while Inductively Coupled Plasma-Mass Spectrometer measured silver ion release.
Results: The experimental group showed significantly higher inhibition zones for all follow-up results. For water sorption test, the higher values were in the experimental group after 1 and 3 months. While for the solubility the higher values were in the experimental group after all follow-ups. Regarding fluoride ion release, comparison between both groups showed no significant difference after all follow-ups. For the silver ion release, results showed significant difference regarding all follow-ups with higher values in the experimental group. Conclusions: Compomers incorporated with 0.025ml silver nanoparticles is promising antibacterial restoration against Streptococcus mutans.

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Advanced Dental Journal
Volume 6, Issue 2
April 2024
Pages 252-261

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