Evaluation of Caries Preventive Potential of Preventive Regimens Containing Herbal-Based or Fluoride-Based Toothpastes Versus Fluoride Varnish and Fluoride Toothpaste Only in High Caries Risk Patients: Randomized Clinical Trial

Document Type : Original Article


1 MSc student conservative dentistry department, Faculty of Dentistry, Cairo University, Cairo, Egypt

2 Conservative Dentistry department, faculty of Dentistry, Cairo University, Egypt

3 Prof of Conservative dentistry dept,Faculty of Dentistry.Cairo University, Cairo,Egypt.


Aim: This study was conducted to assess the caries preventive effect of different preventive regimens using herbal toothpaste compared to fluoride toothpaste and fluoride varnish on high caries risk patients. Materials and methods: A three-armed, parallel-groups, randomized, controlled trial was conducted on 54 participants with high caries risk. Participants were randomly allocated into three groups, (Himalaya complete care), fluoride toothpaste (signal) and fluoride toothpaste (Signal) and fluoride varnish (Polimo). Cariogram assessment was done in four intervals: T0: baseline, T1: after one week, T2: after four weeks and T3: after 12 weeks. Data was analyzed using Medcalc software, version 19 for windows (MedCalc Software Ltd, Belgium). A value less than or equal to 0.05 was considered statistically significant and all tests were two tailed. Results: Regarding caries risk, Intergroup comparison have shown no statistically significant difference within different follow up periods. Intragroup comparison has shown statistically significant difference between different follow-up periods (P < 0.0001). Conclusion: In high caries risk patients, caries preventive regimen based on herbal toothpaste has similar clinical performance to those based on fluoride toothpaste and varnish along three months’ follow-up. Clinical significance: In high-caries-risk individuals, preventive regimens comprising various toothpastes have a favorable impact on caries prevention.


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