Comparative Evaluation of the Anti‑plaque and Anti‑gingivitis Effects of Moringa plant and Fluoride Toothpastes among a Group of Children: A Randomized Controlled Study

Document Type : Original Article


1 Pediatric Dentistry and Dental public health, Faculty of Dentistry, Cairo University, Egypt.

2 Pharmaceutical Technology Department, National Research Centre, Cairo, Egypt


Objective: The present study assessed the anti‑plaque and anti‑gingivitis effects, the effect on salivary pH, and participant satisfaction of Moringa plant extract and Fluoride toothpaste among some children aged between 12 to 15 years.
Material and methods: Sixty children were randomly divided into two equal groups: Group 1 (Moringa toothpaste) and Group 2 (Fluoride toothpaste). The assessment was completed using the gingival and plaque indices at baseline, three weeks, and six weeks. A digital pH meter was used to measure the salivary pH. The participants' satisfaction was evaluated by a questionnaire survey.
Results: Upon completion of the 3-and 6-week follow-up, the gingival index scores significantly differ between the two groups with P-values of 6.82E-06 and 3.01E-08, respectively. The plaque index scores significantly changed with P-values equal to 0.00227 and 2.15E-05, respectively. A significant difference in salivary pH levels was demonstrated. The satisfaction survey revealed no statistically significant difference.
Conclusions: Moringa toothpaste had an added effect on plaque, gingivitis, and salivary pH compared to Fluoride toothpaste, with no adverse reactions or difference in participants' satisfaction.


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